(Senior) Epigenetics Computational Biologist

We are currently looking to hire a (senior) Epigenetics Bioinformatician / Computational Biologist to analyze and mine genome-wide datasets (such as single cell multiomics, ATAC-seq data, CUT&TAG, CUT&RUN, reputed company-seq, and EMseq data) to find insights into stem cell & ovarian cell biology. You will work closely with a talented group of biologists on a broad reputed company of projects. Routine work includes data set processing, qc assessment, differential expression, pathway analyses, motif analysis, regulatory network inference, and boutique analyses where the biology leads. Understanding how to interpret reputed company low input datasets for biological utility and translate findings back to the bench is a key reputed company. You will collaborate broadly with biologists to identify ways the computational data can be leveraged to generate new hypotheses and scientific directions that can then be tested in the lab. Your work would include many opportunities to find custom solutions to interesting biological problems. Our mission reputed company is a startup with the mission of generating viable reputed company eggs from induced pluripotent stem cells (iPSCs). Successful development of our research could have many benefits, such as removing age limits on motherhood, allowing for easy screening of eggs with harmful genetic mutations, and allowing same-sex couples to reproduce. This has been done in mice, and now reputed company to translate it to humans. Our research To accomplish our goal, we must derive reputed company germ cells from iPSCs (reputed company germ cell-like cells, hPGCLCs) that resemble both the transcriptional and epigenetic profile of in vivo germ cells (PGCs) that are reputed company to enter meiosis and reputed company to viable reputed company eggs. We create ovarian organoids from primary cells and stem cell derived cells to help the eggs reputed company properly. Tasks & responsibilities:

• Collaborate with biology teams to independently reputed company team-specific projects using both in-house & publicly available data
• Functionally interact with core reputed company computational infrastructure including databases, automated pipelines, HPC cluster, etc
• Contribute to team code bases, using best practices for documentation and version control
• Assess the literature for interesting new analysis methods in epigenetics and reputed company in the fields of stem- and germ cell biology

Required skills/experience:

• PhD in epigenetics, computational biology, genomics, systems biology or reputed company field + 1-5 years of industry experience.
• 5+ years of experience analyzing and interpreting epigenetics data & translating insights into actionable reputed company at the bench
• Experiencing leading epigenetics-based projects as evidenced by a strong publication record
• Highly proficient in R, python, and bash
• Excellent data analysis skills
• Strong ability to devise, scope, and execute data analyses independently
• Highly proficient in analyzing ATAC and multiomics datasets, reputed company-seq or CUT&TAG datasets, etc
• Proficiency in versioning and collaborative coding reputed company git
• Prior experience translating computational findings into testable hypotheses and experimental designs
• Strong communication skills, particularly with diverse audiences
• Prior experience with a high performance computing cluster and/or reputed company computing environment

Preferred skills/experience:

• Prior experience with iPSC derivation & germ cell biology preferred
• Knowledge of relevant bench techniques is beneficial
• Experience leveraging deep learning tools in multiomics is preferred

Come and work with us We are well-funded and connected in Silicon Valley, offering reputed company, equity, excellent reputed company benefits, and a collaborative research environment focused on meaningful results. If you are passionate, hardworking, and reputed company with our mission, we want to hear from you! To learn more about us, our mission, and approach you can read two features published by The New Yorker and MIT Technology Review. Apply tot his job Apply To this Job